Christopher B. Wilson Tobias R. Kollmann – , [1].

Christopher B. Wilson Tobias R. Kollmann
–
,
,
,
,
B
T-
[1].
(
)
,
,
,
3].
,
4–5
B
T,
,
(
. 1).
T-
T-
BB-
2
. 1.
T-
a
5
(a)
T-
2
(b)
T-
.
B-
Ig
(PAMPs)
T-
b
,
TLRs
,
T-
APRIL,
,
APCs,
.
,
T,
Ig
(
).
36
,
(Th) CD4,
B-
BAFF
.
APRIL,
Y)
T-
,
BAFF
(APCs)
APCs.
B-
Ig (
CD40
5
[2,
/
T-
2
.
5
2.
TCD4
.
(TCR,
CD8 TY)
(DCs). DCs
TLRs,
CD28
(PAMPs)
CD80
T-
CD86
,
(
).
,
,
,
T-
,
,
CTL,
DCs,
IFN-7.
).
Th17, Th2
CD8 T-
Th1
,
. CD4 T,
,
(
37
,
CD4 T-
,
,
T,
Th2 (
. 2) [2–4].
(DCs)
,
IL-12p70
,
I
,
CD4 Th1 T-
,
,
.
,
,
,
.
DCs
,
.
,
Th1 CD4 T,
.
,
.
,
,
,
.
38